منابع مشابه
Physical Aspects of Viral Membrane Fusion
Enveloped viruses commonly employ membrane fusion during cell penetration in order to deliver their genetic material across the cell boundary. Large conformational changes in the proteins embedded in the viral membrane play a fundamental role in the membrane fusion process. Despite the tremendously wide variety of viruses that contain membranes, it appears that they all contain membrane fusion ...
متن کاملMechanisms of viral membrane fusion and its inhibition.
Viral envelope glycoproteins promote viral infection by mediating the fusion of the viral membrane with the host-cell membrane. Structural and biochemical studies of two viral glycoproteins, influenza hemagglutinin and HIV-1 envelope protein, have led to a common model for viral entry. The fusion mechanism involves a transient conformational species that can be targeted by therapeutic strategie...
متن کاملInsights into a structure-based mechanism of viral membrane fusion.
A number of different viral spike proteins, responsible for membrane fusion, show striking similarities in their core structures. The prospect of developing a general structure-based mechanism seems plausible in light of these newly determined structures. Influenza hemagglutinin (HA) is the best-studied fusion machine, whose action has previously been described by a hypothetical "spring-loaded"...
متن کاملPhysical and Functional Aspects of Boshrūyeh Mills
Water can be considered to be the reason for existence and the main factor in formation of some of the traditional Iranian architectural structures. Innovative technologies such as [water] mills and water reservoirs etc. can be placed in this category. These structures are the result of the interaction of the previous generations with nature and utilising its various elements. The human of the ...
متن کاملPhysical and Functional Aspects of Boshrūyeh Mills
Water can be considered to be the reason for existence and the main factor in formation of some of the traditional Iranian architectural structures. Innovative technologies such as [water] mills and water reservoirs etc. can be placed in this category. These structures are the result of the interaction of the previous generations with nature and utilising its various elements. The human of the ...
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ژورنال
عنوان ژورنال: The Scientific World JOURNAL
سال: 2009
ISSN: 1537-744X
DOI: 10.1100/tsw.2009.76